I bought some and was determined to eat it regularly. Is a high blood level dangerous? In regards to your question about strontium being taken as a single dose in the COMB study, this is not unusual. Until about 8 years ago, it was assumed that everyone could convert beta-carotene to vitamin A, but we now know that, in fact, the vast majority of us are not able to make this conversion because our genetic inheritance includes slow or completely ineffective versions of the key enzymes responsible for this job. Here are the citations for the studies upon which the COMB researchers based the studys exercise recommendations: Thanks, Hi sml, PMID: 24612329. Osteoblasts: Strontium increases the rate at which these bone-building cells are produced and increases their lifespan It is possible, by the way, to check strontium levels in bone heres a recent paper in which they did just that (abstract below) but I dont think this new X-ray fluorescence 1-125 based system is yet available to us normal folk outside the rarefied realm of research studies. Re being insurance poor I am hoping that Dr. Grout will still be able to be helpful. You can check Your Bones out from any public library if you dont wish to own it or you can run a Google search for foods rich in magnesium), and (2) you can take extra supplemental magnesium. I have added the ones that were removed that apply to your question in my comments below: Strontium is almost twice as large as calcium, and its larger size does affect DXA readings. Guaranteed. A radioactive form of strontium may kill some cancer cells. Since the volunteer had no prior history of strontium based medications or supplementation, baseline natural strontium levels were obtained followed by a 24h measurement of first intake of strontium citrate supplements (680 mg Sr/day). Creatinine is a breakdown product of creatine phosphate in muscle; its usually produced at a fairly constant rate by the body and is eliminated in urine. Re their recommendation of impact exercise for the participants in this study, I believe it was reasonable and helpful here are the reasons why. THANK YOU for the links to these papers! Within 10 months of using AlgaeCal Plus, my 2012 DXA showed BMD 3.2% in my hip, and 6% in my spine from 2011. For that quotation out of Lis thesis article he cites Meunier as the author of the study, and cites him twice : This is the 2004 article Strontium and calcium share a common carrier system in the intestinal wall, which will. Youll find the expiration date for Strontium Boost clearly printed on the bottom of each bottle. No adverse effects. Still, none of the research that I have seen has ever mentioned any adverse effect on thyroid function from natural forms of strontium at a dosage level of 680 mg/day. In other words, for every 10 calcium ions your bones absorb, they will absorb less than 1 strontium ion. My primary care physician started prescribing me the 1mg estradiol, and I also take in addition the AlgaeCal & Strontium Boost. One thing I learned was not to eat any calcium rich foods within a couple of hours of taking the strontium citrate. and not the strontium citrate. In additional to calcium-containing foods, foods that contain alginate (found in kelp) lower strontium absorption, and so do certain medications, including quinolone antibiotics, and medications that contain aluminum hydroxide or magnesium hydroxide. This individual had results that were slightly under 2,000 ng/ml which, in her assessment, is over 4,000 % higher than the upper normal limit of 45.0 ng/ml. Im sorry to hear about sisters! The time, effort, and knowledge which you apply to answering questions is amazing. However, you may have heard some less-than-confidence inspiring things about strontium. Re K2 (MK-7) I dont know how much vitamin D3 YOU need to get your blood levels into optimal range (60-80 ng/mL). Ideally an hour before, or three hours after eating. Best Strontium Citrate. Aside from it, I was diagnosed with a bit high cholesterol level and a bit high of creatinine and on medication for this in one month. Supplements should always be taken with food, both to provide a buffer if your stomach acid production is good and to trigger sufficient stomach acid production if your ability to produce stomach acid has begun to decline. Thank Dr. Joe also for his recommendation. activate vitamin D (vitamin D is converted into its active, hormonal form which is the form in which vitamin D helps us absorb calcium from the digestive tractin the kidneys) Hello Lara, thank you for the information you have provided on this site. If you dont have the book, your library should have it, so you can check it out without having to buy it although it costs less than $10 on Amazon these days. DXA only checks BMD, which is a measure of quantity. Proper calcium balance inside and outside of nerve cells is required for sodium to flow in and out of these cells, and this flow of sodium is the way in which nerves conduct signals to and from the brain. BMD in my spine is up 6%; BMD in my hip/femur is up 3.2%. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Given all this, its surprising that strontium ranelate continues to be authorized and prescribed in Europe, despite the French pharmacoeconomic committees judgment in 2014 that strontium ranelate had insufficient medical benefit, and a highly unfavorable opinion on the use of the drug issued by the European Pharmacovigilance committee in 2015. How quickly our kidneys filter creatinine from the bloodstream, which is called the creatinine clearance rate, provides a measure of how effectively your kidneys are filtering your blood. PMID: 24434614 Could this be a related side effect? Riedel C, Zimmermann EA, Zustin J, et al. I have a hard time with taking the strontium at night. If you follow the dietary recommendations in Your Bones, you will lower your blood pressure along with your risks for virtually all chronic degenerative diseases, and build healthy bones along with overall good health. In this study, 10 female volunteers recruited as part of the Ryerson and McMaster University Strontium (Sr) in Bone Research Study had their bone strontium levels measured as they self-supplemented with strontium supplements of their choice (all used strontium citrate) over a 4-year period. (And I disagree that dairy is necessarily bad. DRESS syndrome is often severe and can result in death if not diagnosed early for which reason, youre urged to see your doctor immediately if you develop a rash after taking strontium ranelate. Thank you for your wonderful advice. Most medical authorities in the field of vitamin D research, e.g., Dr Michael Holick, also check the Vitamin D Council, recommend at least 2,000 IU/day. These are really great questions, and I am so sorry to hear of what you are going through. I sure wish I could just take 1 pill, but reality is that this would not do the job for me. I was wondering if you had seen this article from Univ of Toronto, re lyme (borrelia burgdorferi) causing bone loss? Does anyone have any information about the dangers to my baby? . In Laura Pizzornos blog , she refers to the excretion of ranelic acid , and questions the non excreted portion. In this study, 176 women over 40 years of age followed one of three different bone-health programs: Plan 1 used a bone-health supplement with vitamin D3 (800 IU), AlgaeCals plant-sourced form of calcium (720 mg), and vitamin K as MK-4 (1.5 mg) for one year. Thanks! For the remaining 6 months, the women just exercised at home. So, whats the take-away from this paper by Chen LJ et al.? I believe these will be posted on AlgaeCals website soon. Thanks Mary. That makes sense about the calcium dosage; the online label didnt say how often to take it. HERE is a link to Mayo Clinics discussion of causes of hair loss. This is not nearly enough to take in conjunction with the amount of suggested strontium. The other night I contacted the manufacturer of my strontium and inquired as to if the supplement was better absorbed on an empty stomach or with food. If you can . PMID: 841579. The strontium I take is 1000 mcg. If the latter, I am happy to help you, but please do me the courtesy of citing my work. The fact that strontium ranelate may cause venous thromboembolism and DRESS syndrome (among other nasty effects) strongly suggests otherwise. In patients with chronic renal failure, blood levels of strontium are increased four-fold when creatinine clearance is less than 50 mL/minute. Please feel free to contact our Bone Health Consultants 7 days a week at 1-800-820-0184 (USA & Canada, toll-free) or email [emailprotected] for more information and personalized support! Either product will be fine. So it is best to take a supplement. Dont worry about strontium taking the place of calcium in your bones. Heres a recent paper on this: Pharm Res. MK-4, even at such a low dose, cant hurt and may help. Strontium does indeed increase our absorption of calcium, which increases our need for magnesium (important for muscle and nerve function). 2006 Aug;23(8):1675-86. In contrast, ranelic acid is an unnatural, lately created in a lab, compound, which, the research indicates, increases your risk for venous thromboembolism and DRESS syndrome, among other unpleasant side effects. For additional sources on its toxicity go to Toxin Profiles and theAgency for Toxic Substances & Disease Registry. Both strontium and citrate are natural substances that are highly beneficial to and are utilized within the body ideally, the majority of the strontium in strontium citrate supplements is absorbed into bone, increasing bone mass and strength. Should I introduce the strontium gradually, building up from one pill to two to three over a period of time or should I take one pill three times a day? Epub 2011 Dec 15. If it does replace calcium, where does the 1200 mg of calcium go? Thanks for sharing this research! My question is should I take 1 or 2 capsules of Strontium, given that my DEXA results are in the normal range? Strontium is the singular ingredient that makes Ultimate Bone Support (UBS) a superior supplement to conserve bones. I wonder if the interval, between Calcium intakes is too short. I heard it was not good to take it so long. Rely on Science, not rumor. When I tried both Algae Cal and Strontium as suggested I developed Gi loose bowels and discomfort. How old are you? Shaine, Hi Shaine, Interesting that my calcium was high and I have never taken calcium supplements until quite recently. Hi Jeanette, At age 48, you are perimenopausal. What issues have you had that have lead you to these choices? If thats so, how could you possibly come up with an accurate number? 2003;14 Suppl 3:S19-24. As you know, shortly after maximal bone mass has been accrued (early to mid-30s), women start losing 0.5-1% of their BMD annually, a loss that accelerates to 2% or more during menopause and continues for as many as 10 years afterwards. Many people need 5,000 IU of vit D3 daily to achieve these levels. Excellent material. So, I have finally read the paper but I found no mention of a 170 mg dose of strontium being used. Thanks for your response about New Chapter. Meunier, P. J., Roux, C., Seeman, E., Ortolani, S., Badurski, J. E., Spector, T. D., Our active intestinal absorption of strontium is vitamin D-dependent and decreases with aging, and with consumption of phosphate additives as well as calcium. Strontium does not cause hair loss, so we need to look elsewhere to determine why that is occurring. They can provide tailored information based on the specific medications youre taking. I have just found out that a dear friend has a rare bone cancer Osteasarcoom. The best time to take fat-soluble vitamins like vitamin D, A, and K is with a meal containing fats. You want both of these to be used inside your body the strontium, to build bone, and the citrate, to help make your overall pH more alkaline. Keep me posted on how you are doing and dont hesitate to get in touch if I can be helpful. After reading the abstract, I did not pull the full article.). ( I hope you are eating lots of these vegetables like spinach, kale, Swiss chard, broccoli because they contain not only calcium but other minerals and vitamins essential for building healthy bones (e.g., vitamin K1, magnesium, boron). YOUR best solution is highly likely to be around 180 mcg of K2 as MK-7. The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a novel agent in the treatment of postmenopausal osteoporosis. Meal containing fats a low dose, cant hurt and may help refers... 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